Drake May is the standout stock-up, pacing as a top fantasy QB with a favorable matchup slate and a diversified Patriots attack that fed multiple receivers. Cam Scataboo erupted for the Giants, while Rico Dott and Chuba Hubbard kept Carolina in wins with a backfield-by-committee approach that still favored volume. The backfield reshuffles continued with Kamani Vidal taking over in San Diego’s run game, complemented by Devin Achan and Jaylen Waddle supplying steady fantasy floors for Miami.

Injury news drove waiver-wires: Puka Nacua’s London outing and Kyler Murray’s crew faced questions, while PPR-friendly targets like Demario Douglas, Stefon Diggs, and Travis Etienne remained reliable in solid matchups. The Chiefs’ Kelce-Rashii Rice stack remained a staple, and the Jets’ offense added via Joe Flacco and Bryce Young/CJ Stroud debate left managers weighing ceiling vs. risk. Deliberate pickups included Bam Knight and Cameron Johnson, with Streaks and schedules guiding who gets the edge down the stretch.

Week six delivered a chaotic fantasy landscape with a rash of injuries and a handful of breakout performances. Brian Thomas Jr. delivered a true breakout, Kamani Vidal seized a lead back role with a strong showing, and Derrick Henry finally supplied a usable line after a drought. Puka Nakua and DK Metcalf weathered injury chatter with returns that mattered for shiny matchups, while the waivers loom with potential every week.

Key takeaways: chase backfield opportunities where a lead can flip, decide if Brian Thomas Jr. is a hold or a sell high after a red-hot game, monitor rest-of-season schedules for rookies, and weigh the odds on veterans like Henry and Metcalf amid shifting spreads and injury notes as we move toward the fantasy playoffs.